Yissum — Hebrew University's Technology Transfer Company
Israel
Founded in 1964, Yissum is one of the world's first university tech-transfer firms; it has spun off 80+ companies including …
Israel · Rehovot · See the Israel profile
Founded in 1959 as the Weizmann Institute's commercial arm, Yeda has generated over USD 2 billion in licensing revenue in a recent six-year period — some 80-90% from three inventions, led by the MS drug Copaxone — and returns about 40% of royalties to inventor-researchers.
Yeda Research and Development Company was founded in 1959 as the commercial arm of the Weizmann Institute of Science in Rehovot, Israel, tasked with licensing the Institute's scientific discoveries to industry and returning the proceeds to further research.
Yeda has generated over USD 2 billion in licensing revenue in a recent six-year period and historically more than NIS 1 billion in royalties, consistently ranking among the top five academic institutions worldwide for royalty income. Some 80-90% of that income traces to just three inventions: the multiple sclerosis drug Copaxone (glatiramer acetate, discovered by Michael Sela, Ruth Arnon and Dvora Teitelbaum, licensed to Teva in 1987 and FDA-approved in 1996), the MS drug Rebif (licensed to Serono), and an NDS satellite-broadcast encryption system. Yeda passes roughly 40% of royalty income back to the inventing researchers, reinvesting the rest in the Institute.
Yeda is one of the world's oldest and most successful university technology-transfer offices, built on a 65-year track record of turning basic science into licensed products. But its revenue is a hit-driven model concentrated in a handful of blockbuster licences rather than a broad, diversified portfolio — a pattern that is hard to replicate deliberately and depends on a research institute of Weizmann's calibre.
Read the full analysis: https://israelvalley.com/2026/03/31/the-weizmann-institutes-innovation-and-technology-transfer-office/
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Israel
Founded in 1964, Yissum is one of the world's first university tech-transfer firms; it has spun off 80+ companies including …
Belgium
KU Leuven's LRD office has backed 199 university spin-offs since the 1980s, employing 7,700+ people; ranked Europe's most innovative university …
South Africa
Since 2000, UCT's Research Contracts & Innovation office has built 40 spin-off companies worth over R250 million in university equity, …
Switzerland
ETH Zurich's tech-transfer office produced 37 new spin-offs in 2024, which attracted almost CHF 425 million in financing that year …
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